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TopWeightLoss.us
Last Updated: October 2026

Best Semaglutide Providers of 2026

Semaglutide, the active ingredient in Ozempic and Wegovy, is one of the most effective GLP-1 medications for weight loss. Use the comparison below to weigh each provider's price, medical support and medication options.

Licensed CliniciansHighly Rated PicksQuick Online Intake
Francheska Capistrano, Medical Content Reviewer

Francheska Capistrano, RMT, MPH

Clinically checked · Our review process

Our Most Popular
1
embody logo

Exceptional

9.8out of 10

Semaglutide from $69/mo, delivered in 1-2 days

Refund if not approvedFree expedited shipping

Treatments offered

Compounded semaglutide injection (GLP-1) · Compounded tirzepatide injection (GLP-1 + GIP) · Online doctor review and prescription · Dose changes through the patient portal

Starting price

$79$69/month

Semaglutide $69/mo · month-to-month

*Compounded medications are not FDA-approved.

  • Semaglutide $69/mo; tirzepatide $119/mo
  • 5-minute questionnaire; doctor review usually within 24 hours
  • Free 1-2 day shipping: cold-packed, tracked and insured
  • No insurance, no clinic visits, cancel anytime

from $69/month

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3.8Trustpilot(9,604)

embody prescribes compounded semaglutide at $69/mo and tirzepatide at $119/mo online, ships in 1-2 days, and requires no insurance. Trustpilot: 3.8 from 9,604 reviews.

Read full embody review
2
altRx logo

Exceptional

9.7out of 10

Low-cost GLP-1 care: semaglutide from $89/mo

Clear, flat pricingNo insurance needed

Treatments offered

Compounded semaglutide injection (GLP-1) · Compounded tirzepatide injection (GLP-1 + GIP) · Brand-name Ozempic, Zepbound and Wegovy · Once-weekly injection schedule

Starting price

$199$89/month

Semaglutide $89/mo · flat at every dose

*Compounded medications are not FDA-approved.

  • Semaglutide from $89/mo; tirzepatide from $149/mo
  • Brand-name Ozempic, Zepbound and Wegovy available
  • Reviewed by a physician, PA or nurse practitioner
  • Free shipping, arriving in about 5-7 days

from $89/month

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altRx sells compounded semaglutide from $89/month and tirzepatide from $149/month at a flat price per dose, plus brand-name Ozempic, Zepbound and Wegovy. Self-pay, no insurance needed.

Read full altRx review
3
Eden logo

Excellent

9.6out of 10

Flat-price GLP-1: semaglutide $99/mo, tirzepatide $129/mo at every dose

One price at every doseNo membership or long-term plan

Treatments offered

Compounded semaglutide injection (GLP-1) · Compounded tirzepatide injection (GLP-1 + GIP) · Doctor-guided dosing and ongoing clinical care · Human support available 24/7

Starting price

$99/month

Semaglutide $99/mo · flat every month, every dose; no membership

*Compounded medications are not FDA-approved.

  • Semaglutide $99/month, the same at every dose
  • Tirzepatide $129/month, the same at every dose
  • All-inclusive price: no membership, annual or long-term plan
  • Doctor-guided care with 24/7 human support

from $99/month

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4.5Trustpilot(4,917)

Eden charges one flat price at every dose: compounded semaglutide $99/month and tirzepatide $129/month, with no annual plan, doctor-guided care and 24/7 human support. Trustpilot: 4.5 from 4,917 reviews.

Read full Eden review
4
welludr logo

Excellent

9.4out of 10

Compounded semaglutide from $49/month and tirzepatide from $89/month

1,000,000+ patientsWeight-loss warranty

Treatments offered

Compounded semaglutide injection (GLP-1) · Compounded tirzepatide injection (GLP-1 + GIP) · Brand-name Ozempic and Zepbound · Online provider review and prescription

Starting price

$49/month

Semaglutide $49/mo · 12-month plan; same price at every dose

*Compounded medications are not FDA-approved.

  • Semaglutide from $49/mo; tirzepatide from $89/mo
  • Same price at every dose; ships every 4 weeks
  • Brand-name Ozempic and Zepbound also offered
  • Board-certified specialists plus a Medical Weight-Care Coach

from $49/month

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4.6Trustpilot(2,188)

welludr offers compounded semaglutide from $49/mo and tirzepatide from $89/mo, plus brand-name options, with board-certified specialists and a weight-loss warranty. Trustpilot: 4.6 from 2,188 reviews.

Read full welludr review
5
ro logo

Excellent

9.3out of 10

Online weight loss care from an established telehealth brand

Treatments offered

Compounded semaglutide · Brand-name GLP-1 medication · Metabolic support supplements · Dose changes guided by your provider

Verified price

Semaglutide: Brand-name Wegovy: pill from $149/mo or pen from $199, plus membership

  • Consultations with board-certified providers
  • Several GLP-1 medication options
  • In-house pharmacy with home delivery
  • Ongoing care and dose adjustments
Visit SiteRead full review
3.9Trustpilot(7,105)

ro is a well-known telehealth company offering online weight loss treatment, with licensed providers, GLP-1 prescriptions and home delivery from its own pharmacy.

Read full ro review
6
TrimRx logo

Excellent

9.1out of 10

Custom-dosed GLP-1 plans with ongoing provider check-ins

HIPAA compliantMade in the USA

Treatments offered

Compounded semaglutide injection (GLP-1) · Compounded tirzepatide injection (GLP-1 + GIP) · Dosing schedule customized by your provider · Unlimited check-ins for the length of treatment

Starting price

$289$149/month

Semaglutide $149/mo · same price at every dose; $140 discount applied

*Compounded medications are not FDA-approved.

  • Semaglutide $149/month at every dose
  • Tirzepatide $259/month
  • Custom dosing plus unlimited provider check-ins
  • Free consultation and tracked delivery, often next-day

from $149/month

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3.8Trustpilot(5,392)

TrimRx offers custom-dosed compounded semaglutide at $149/month (same at every dose) and tirzepatide at $259/month, with unlimited provider check-ins included. Trustpilot: 3.8 from 5,392 reviews.

Read full TrimRx review
7
SHED logo

Very Good

8.9out of 10

20% off your first month of GLP-1 treatment

Lose 5% in 120 days or money backFully online visit and checkout

Treatments offered

Compounded semaglutide injection (GLP-1) · Compounded tirzepatide injection (GLP-1 + GIP) · Health coaching on every plan · Progress tracking and regular check-ins

Starting price

$199/month

Semaglutide $199/mo · 20% off month one; coaching included

*Compounded medications are not FDA-approved.

  • Semaglutide from $199/mo; tirzepatide from $299/mo
  • First month 20% off
  • Health coaching included with every plan
  • Money back if you do not lose 5% of body weight in 120 days

from $199/month

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4.6Trustpilot(1,134)

SHED pairs compounded semaglutide (from $199/mo) and tirzepatide (from $299/mo) with included health coaching, 20% off month one and a 5%-in-120-days money-back guarantee. Trustpilot: 4.6 from 1,134 reviews.

Read full SHED review
8
Medvi logo

Very Good

8.5out of 10

Prescription weight loss without the hassle

HSA/FSA approvedNo membership or hidden fees

Treatments offered

Weekly semaglutide (GLP-1) injections · Weekly tirzepatide (GLP-1/GIP) injections · Daily oral dissolving GLP-1 tablets, no needles · Video visits, free dietitian access and care coaching

Starting price

$199$99/month

Semaglutide $99/mo · promo; all-inclusive with coaching

  • Semaglutide (GLP-1) injections from $99/month (normally $199)
  • Tirzepatide (GLP-1/GIP) injections from $166/month (normally $299)
  • Needle-free daily dissolving GLP-1 tablets at $249/month
  • Video visits, free dietitian access and care coaching

from $99/month

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4.3Trustpilot(14,987)

Medvi bundles provider visits, medication, free dietitian access and care coaching into one price: semaglutide from $99/mo (reg. $199), tirzepatide from $166/mo (reg. $299). HSA/FSA approved. Trustpilot: 4.3 from 14,987 reviews.

Read full Medvi review
9
Sprout logo

Very Good

8.4out of 10

$200 off your first month of GLP-1 care

$200 off month oneShips within 2 days

Treatments offered

Compounded semaglutide injection (GLP-1) · Compounded tirzepatide injection (GLP-1 + GIP) · Brand-name Wegovy (semaglutide) pen · Personalized treatment plans guided by a provider

Starting price

$149/month

Semaglutide $149/mo · starting price

*Compounded medications are not FDA-approved.

  • Semaglutide from $149/mo
  • Tirzepatide from $199/mo
  • Brand-name Wegovy from $1,799/mo
  • Prescriptions ship within 2 days

from $149/month

Visit SiteRead full review
4.1Trustpilot(188)

Sprout offers personalized GLP-1 plans with compounded semaglutide from $149/mo, tirzepatide from $199/mo and brand-name Wegovy, and ships prescriptions within 2 days.

Read full Sprout review

What is semaglutide and how does it work?

Semaglutide is a GLP-1 receptor agonist: it copies a natural gut hormone to curb appetite and help regulate blood sugar. It was first developed for type 2 diabetes, sold as Ozempic, and was later approved for chronic weight management as Wegovy. For the full mechanism, see how GLP-1 medications work.

How much weight do people lose on semaglutide?

Participants in the STEP clinical trials lost an average of 15% of their body weight over 68 weeks on semaglutide. Individual results vary, but most people notice a smaller appetite within the first two weeks. Our guide to your first month on weight loss medication walks through what comes next.

What should you look for in a semaglutide provider?

Semaglutide providers differ widely on price, medical oversight and medication quality. We scored each one on transparency, clinical support and overall value. Before you sign up, read our guide to choosing a telehealth weight loss provider. At minimum, look for:

  • Prescriptions from licensed medical providers
  • One clear, all-inclusive monthly price
  • A choice of compounded or brand-name medication
  • Clinical support that continues after your first order

Should you choose semaglutide or tirzepatide?

Both medications work well for weight loss, but tirzepatide acts on two hormone receptors while semaglutide acts on one. Our semaglutide vs tirzepatide comparison covers the differences in detail, and our tirzepatide providers page lists where to get the alternative.

Our rankings are rechecked on a rolling basis. For deeper research, read our weight loss guides, or answer a few quick questions to get a provider suggestion that fits your goals and budget.

Related GLP-1 guides

Every other weight loss medication guide on Top Weight Loss, each built on prices we have checked ourselves.

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