Last Updated: October 2026

Best Online Weight Loss Programs of 2026

Prescription GLP-1 care, guided by clinicians, from home

Today's online weight loss programs pair prescription GLP-1 medication with full medical oversight, all without leaving home. We compared the leading programs on price, clinical support and results.

Licensed CliniciansHighly Rated PicksQuick Online Intake

Reviewed for medical accuracy by Francheska Capistrano, RMT, MPH · Medical Content Reviewer

Clinically checked Checked Oct 22, 2026 · Author: Top Weight Loss Research Team · Our review process

Our Most Popular

Exceptional

9.8out of 10

Semaglutide from $69/mo, delivered in 1-2 days

Refund if not approvedFree expedited shippingNo hidden fees

Treatments offered

Compounded semaglutide injection (GLP-1) · Compounded tirzepatide injection (GLP-1 + GIP) · Online doctor review and prescription · Dose changes through the patient portal

Starting price

$79$69/month

Semaglutide $69/mo · Tirzepatide $119/mo

*Compounded medications are not FDA-approved.

Semaglutide $69/mo; tirzepatide $119/mo
5-minute questionnaire; doctor review usually within 24 hours
Free 1-2 day shipping: cold-packed, tracked and insured
No insurance, no clinic visits, cancel anytime

Pricing starts at

from $69/month

Visit Site Read full review

3.8Trustpilot(9,604)

embody prescribes compounded semaglutide at $69/mo and tirzepatide at $119/mo online, ships in 1-2 days, and requires no insurance. Trustpilot: 3.8 from 9,604 reviews.

Read full embody review

Exceptional

9.7out of 10

Low-cost GLP-1 care: semaglutide from $89/mo

Clear, flat pricingNo insurance neededBuy Now, Pay Later

Treatments offered

Compounded semaglutide injection (GLP-1) · Compounded tirzepatide injection (GLP-1 + GIP) · Brand-name Ozempic, Zepbound and Wegovy · Once-weekly injection schedule

Starting price

$199$89/month

Semaglutide $89/mo · Tirzepatide $149/mo

*Compounded medications are not FDA-approved.

Semaglutide from $89/mo; tirzepatide from $149/mo
Brand-name Ozempic, Zepbound and Wegovy available
Reviewed by a physician, PA or nurse practitioner
Free shipping, arriving in about 5-7 days

Pricing starts at

from $89/month

Visit Site Read full review

altRx sells compounded semaglutide from $89/month and tirzepatide from $149/month at a flat price per dose, plus brand-name Ozempic, Zepbound and Wegovy. Self-pay, no insurance needed.

Read full altRx review

Excellent

9.6out of 10

Flat-price GLP-1: semaglutide $99/mo, tirzepatide $129/mo at every dose

One price at every doseNo membership or long-term plan24/7 human support

Treatments offered

Compounded semaglutide injection (GLP-1) · Compounded tirzepatide injection (GLP-1 + GIP) · Doctor-guided dosing and ongoing clinical care · Human support available 24/7

Starting price

$99/month

Semaglutide $99/mo · Tirzepatide $129/mo

*Compounded medications are not FDA-approved.

Semaglutide $99/month, the same at every dose
Tirzepatide $129/month, the same at every dose
All-inclusive price: no membership, annual or long-term plan
Doctor-guided care with 24/7 human support

Pricing starts at

from $99/month

Visit Site Read full review

4.5Trustpilot(4,917)

Eden charges one flat price at every dose: compounded semaglutide $99/month and tirzepatide $129/month, with no annual plan, doctor-guided care and 24/7 human support. Trustpilot: 4.5 from 4,917 reviews.

Read full Eden review

Excellent

9.4out of 10

Compounded semaglutide from $49/month and tirzepatide from $89/month

1,000,000+ patientsWeight-loss warrantyOne price at every dose

Treatments offered

Compounded semaglutide injection (GLP-1) · Compounded tirzepatide injection (GLP-1 + GIP) · Brand-name Ozempic and Zepbound · Online provider review and prescription

Starting price

$49/month

Semaglutide $49/mo · Tirzepatide $89/mo

*Compounded medications are not FDA-approved.

Semaglutide from $49/mo; tirzepatide from $89/mo
Same price at every dose; ships every 4 weeks
Brand-name Ozempic and Zepbound also offered
Board-certified specialists plus a Medical Weight-Care Coach

Pricing starts at

from $49/month

Visit Site Read full review

4.6Trustpilot(2,188)

welludr offers compounded semaglutide from $49/mo and tirzepatide from $89/mo, plus brand-name options, with board-certified specialists and a weight-loss warranty. Trustpilot: 4.6 from 2,188 reviews.

Read full welludr review

Excellent

9.3out of 10

Online weight loss care from an established telehealth brand

Treatments offered

Compounded semaglutide · Brand-name GLP-1 medication · Metabolic support supplements · Dose changes guided by your provider

Consultations with board-certified providers
Several GLP-1 medication options
In-house pharmacy with home delivery
Ongoing care and dose adjustments

Visit Site Read full review

3.9Trustpilot(7,105)

ro is a well-known telehealth company offering online weight loss treatment, with licensed providers, GLP-1 prescriptions and home delivery from its own pharmacy.

Read full ro review

Excellent

9.1out of 10

Custom-dosed GLP-1 plans with ongoing provider check-ins

HIPAA compliantMade in the USAFree tracked shipping

Treatments offered

Compounded semaglutide injection (GLP-1) · Compounded tirzepatide injection (GLP-1 + GIP) · Dosing schedule customized by your provider · Unlimited check-ins for the length of treatment

Starting price

$289$149/month

Semaglutide $149/mo · Tirzepatide $259/mo

*Compounded medications are not FDA-approved.

Semaglutide $149/month at every dose
Tirzepatide $259/month
Custom dosing plus unlimited provider check-ins
Free consultation and tracked delivery, often next-day

Pricing starts at

from $149/month

Visit Site Read full review

3.8Trustpilot(5,392)

TrimRx offers custom-dosed compounded semaglutide at $149/month (same at every dose) and tirzepatide at $259/month, with unlimited provider check-ins included. Trustpilot: 3.8 from 5,392 reviews.

Read full TrimRx review

Very Good

8.9out of 10

20% off your first month of GLP-1 treatment

Lose 5% in 120 days or money backFully online visit and checkoutCoaching included

Treatments offered

Compounded semaglutide injection (GLP-1) · Compounded tirzepatide injection (GLP-1 + GIP) · Health coaching on every plan · Progress tracking and regular check-ins

Starting price

$199/month

Semaglutide $199/mo · Tirzepatide $299/mo

*Compounded medications are not FDA-approved.

Semaglutide from $199/mo; tirzepatide from $299/mo
First month 20% off
Health coaching included with every plan
Money back if you do not lose 5% of body weight in 120 days

Pricing starts at

from $199/month

Visit Site Read full review

4.6Trustpilot(1,134)

SHED pairs compounded semaglutide (from $199/mo) and tirzepatide (from $299/mo) with included health coaching, 20% off month one and a 5%-in-120-days money-back guarantee. Trustpilot: 4.6 from 1,134 reviews.

Read full SHED review

Very Good

8.5out of 10

Prescription weight loss without the hassle

HSA/FSA approvedNo membership or hidden feesFree shipping

Treatments offered

Weekly semaglutide (GLP-1) injections · Weekly tirzepatide (GLP-1/GIP) injections · Daily oral dissolving GLP-1 tablets, no needles · Video visits, free dietitian access and care coaching

Starting price

$199$99/month

Semaglutide $99/mo · Tirzepatide $166/mo

Semaglutide (GLP-1) injections from $99/month (normally $199)
Tirzepatide (GLP-1/GIP) injections from $166/month (normally $299)
Needle-free daily dissolving GLP-1 tablets at $249/month
Video visits, free dietitian access and care coaching

Pricing starts at

from $99/month

Visit Site Read full review

4.3Trustpilot(14,987)

Medvi bundles provider visits, medication, free dietitian access and care coaching into one price: semaglutide from $99/mo (reg. $199), tirzepatide from $166/mo (reg. $299). HSA/FSA approved. Trustpilot: 4.3 from 14,987 reviews.

Read full Medvi review

Very Good

8.4out of 10

$200 off your first month of GLP-1 care

$200 off month oneShips within 2 daysPersonalized plans

Treatments offered

Compounded semaglutide injection (GLP-1) · Compounded tirzepatide injection (GLP-1 + GIP) · Brand-name Wegovy (semaglutide) pen · Personalized treatment plans guided by a provider

Starting price

$149/month

Semaglutide $149/mo · Tirzepatide $199/mo

*Compounded medications are not FDA-approved.

Semaglutide from $149/mo
Tirzepatide from $199/mo
Brand-name Wegovy from $1,799/mo
Prescriptions ship within 2 days

Pricing starts at

from $149/month

Visit Site Read full review

4.1Trustpilot(188)

Sprout offers personalized GLP-1 plans with compounded semaglutide from $149/mo, tirzepatide from $199/mo and brand-name Wegovy, and ships prescriptions within 2 days.

Read full Sprout review

Very Good

8.2out of 10

Get started today for $147

Treatments offered

Compounded semaglutide · Compounded tirzepatide · Dosing optimized by algorithm · Treatment changes informed by your data

Treatment matching driven by algorithms
Licensed provider consultations included
Personalized GLP-1 medication plans
Progress tracking based on your data

Visit Site Read full review

Wellorithm uses algorithms and patient data to recommend GLP-1 treatment plans, with licensed providers overseeing every prescription.

Read full Wellorithm review

How does an online weight loss program work?

An online weight loss program combines a prescription GLP-1 medication with telehealth visits, ongoing medical support and home delivery. You fill out a health evaluation online, a licensed provider reviews it, and your medication arrives at your door. Our guide to your first month on medication covers each stage.

Complete a medical evaluation online
A licensed physician writes the prescription
Medication ships straight to you
Regular clinical check-ins continue

What makes one online weight loss program better than another?

Medical oversight, clear pricing and ongoing support separate the best programs from the rest. Top programs cover the medication, consultations and follow-up care in a single monthly fee. Before enrolling, read how to evaluate a telehealth provider.

Which GLP-1 medications do online programs prescribe?

Most leading programs prescribe semaglutide (Ozempic/Wegovy), tirzepatide (Mounjaro/Zepbound), or both. These are the two most effective GLP-1 medications for weight loss. Some programs offer both and others focus on one. Our tirzepatide vs semaglutide guide explains the differences.

Who qualifies for an online GLP-1 weight loss program?

Most programs require a BMI of 30 or higher, or a BMI of 27 or higher with a weight-related health condition. Your medical history, current medications and overall health are reviewed too. Read the full eligibility guide, or take our quiz to find the program that fits you.

Our rankings are rechecked on a rolling basis. For deeper research, read our weight loss guides, or answer a few quick questions to get a provider suggestion that fits your goals and budget.

Related GLP-1 guides

Every other weight loss medication guide on Top Weight Loss, each built on prices we have checked ourselves.

Best Online Weight Loss Programs of 2026

Prescription GLP-1 care, guided by clinicians, from home

Semaglutide from $69/mo, delivered in 1-2 days

Low-cost GLP-1 care: semaglutide from $89/mo

Flat-price GLP-1: semaglutide $99/mo, tirzepatide $129/mo at every dose

Compounded semaglutide from $49/month and tirzepatide from $89/month

Online weight loss care from an established telehealth brand

Custom-dosed GLP-1 plans with ongoing provider check-ins

20% off your first month of GLP-1 treatment

Prescription weight loss without the hassle

$200 off your first month of GLP-1 care

Get started today for $147

How does an online weight loss program work?

What makes one online weight loss program better than another?

Which GLP-1 medications do online programs prescribe?

Who qualifies for an online GLP-1 weight loss program?

Related GLP-1 guides

FAQs