Last Updated: October 2026

Best Weight Loss Injections of 2026

Injectable GLP-1 treatments, compared side by side

In clinical trials, GLP-1 injections such as semaglutide and tirzepatide produced 15-22.5% average weight loss. Compare the providers that offer injectable treatment programs below.

Licensed CliniciansHighly Rated PicksQuick Online Intake

Reviewed for medical accuracy by Francheska Capistrano, RMT, MPH · Medical Content Reviewer

Clinically checked Checked Oct 22, 2026 · Author: Top Weight Loss Research Team · Our review process

Our Most Popular

Exceptional

9.8out of 10

Semaglutide from $69/mo, delivered in 1-2 days

Refund if not approvedFree expedited shippingNo hidden fees

Treatments offered

Compounded semaglutide injection (GLP-1) · Compounded tirzepatide injection (GLP-1 + GIP) · Online doctor review and prescription · Dose changes through the patient portal

Starting price

$79$69/month

Semaglutide $69/mo · Tirzepatide $119/mo

*Compounded medications are not FDA-approved.

Semaglutide $69/mo; tirzepatide $119/mo
5-minute questionnaire; doctor review usually within 24 hours
Free 1-2 day shipping: cold-packed, tracked and insured
No insurance, no clinic visits, cancel anytime

Pricing starts at

from $69/month

Visit Site Read full review

3.8Trustpilot(9,604)

embody prescribes compounded semaglutide at $69/mo and tirzepatide at $119/mo online, ships in 1-2 days, and requires no insurance. Trustpilot: 3.8 from 9,604 reviews.

Read full embody review

Exceptional

9.7out of 10

Low-cost GLP-1 care: semaglutide from $89/mo

Clear, flat pricingNo insurance neededBuy Now, Pay Later

Treatments offered

Compounded semaglutide injection (GLP-1) · Compounded tirzepatide injection (GLP-1 + GIP) · Brand-name Ozempic, Zepbound and Wegovy · Once-weekly injection schedule

Starting price

$199$89/month

Semaglutide $89/mo · Tirzepatide $149/mo

*Compounded medications are not FDA-approved.

Semaglutide from $89/mo; tirzepatide from $149/mo
Brand-name Ozempic, Zepbound and Wegovy available
Reviewed by a physician, PA or nurse practitioner
Free shipping, arriving in about 5-7 days

Pricing starts at

from $89/month

Visit Site Read full review

altRx sells compounded semaglutide from $89/month and tirzepatide from $149/month at a flat price per dose, plus brand-name Ozempic, Zepbound and Wegovy. Self-pay, no insurance needed.

Read full altRx review

Excellent

9.6out of 10

Flat-price GLP-1: semaglutide $99/mo, tirzepatide $129/mo at every dose

One price at every doseNo membership or long-term plan24/7 human support

Treatments offered

Compounded semaglutide injection (GLP-1) · Compounded tirzepatide injection (GLP-1 + GIP) · Doctor-guided dosing and ongoing clinical care · Human support available 24/7

Starting price

$99/month

Semaglutide $99/mo · Tirzepatide $129/mo

*Compounded medications are not FDA-approved.

Semaglutide $99/month, the same at every dose
Tirzepatide $129/month, the same at every dose
All-inclusive price: no membership, annual or long-term plan
Doctor-guided care with 24/7 human support

Pricing starts at

from $99/month

Visit Site Read full review

4.5Trustpilot(4,917)

Eden charges one flat price at every dose: compounded semaglutide $99/month and tirzepatide $129/month, with no annual plan, doctor-guided care and 24/7 human support. Trustpilot: 4.5 from 4,917 reviews.

Read full Eden review

Excellent

9.4out of 10

Compounded semaglutide from $49/month and tirzepatide from $89/month

1,000,000+ patientsWeight-loss warrantyOne price at every dose

Treatments offered

Compounded semaglutide injection (GLP-1) · Compounded tirzepatide injection (GLP-1 + GIP) · Brand-name Ozempic and Zepbound · Online provider review and prescription

Starting price

$49/month

Semaglutide $49/mo · Tirzepatide $89/mo

*Compounded medications are not FDA-approved.

Semaglutide from $49/mo; tirzepatide from $89/mo
Same price at every dose; ships every 4 weeks
Brand-name Ozempic and Zepbound also offered
Board-certified specialists plus a Medical Weight-Care Coach

Pricing starts at

from $49/month

Visit Site Read full review

4.6Trustpilot(2,188)

welludr offers compounded semaglutide from $49/mo and tirzepatide from $89/mo, plus brand-name options, with board-certified specialists and a weight-loss warranty. Trustpilot: 4.6 from 2,188 reviews.

Read full welludr review

Excellent

9.3out of 10

Online weight loss care from an established telehealth brand

Treatments offered

Compounded semaglutide · Brand-name GLP-1 medication · Metabolic support supplements · Dose changes guided by your provider

Consultations with board-certified providers
Several GLP-1 medication options
In-house pharmacy with home delivery
Ongoing care and dose adjustments

Visit Site Read full review

3.9Trustpilot(7,105)

ro is a well-known telehealth company offering online weight loss treatment, with licensed providers, GLP-1 prescriptions and home delivery from its own pharmacy.

Read full ro review

Excellent

9.1out of 10

Custom-dosed GLP-1 plans with ongoing provider check-ins

HIPAA compliantMade in the USAFree tracked shipping

Treatments offered

Compounded semaglutide injection (GLP-1) · Compounded tirzepatide injection (GLP-1 + GIP) · Dosing schedule customized by your provider · Unlimited check-ins for the length of treatment

Starting price

$289$149/month

Semaglutide $149/mo · Tirzepatide $259/mo

*Compounded medications are not FDA-approved.

Semaglutide $149/month at every dose
Tirzepatide $259/month
Custom dosing plus unlimited provider check-ins
Free consultation and tracked delivery, often next-day

Pricing starts at

from $149/month

Visit Site Read full review

3.8Trustpilot(5,392)

TrimRx offers custom-dosed compounded semaglutide at $149/month (same at every dose) and tirzepatide at $259/month, with unlimited provider check-ins included. Trustpilot: 3.8 from 5,392 reviews.

Read full TrimRx review

Very Good

8.9out of 10

20% off your first month of GLP-1 treatment

Lose 5% in 120 days or money backFully online visit and checkoutCoaching included

Treatments offered

Compounded semaglutide injection (GLP-1) · Compounded tirzepatide injection (GLP-1 + GIP) · Health coaching on every plan · Progress tracking and regular check-ins

Starting price

$199/month

Semaglutide $199/mo · Tirzepatide $299/mo

*Compounded medications are not FDA-approved.

Semaglutide from $199/mo; tirzepatide from $299/mo
First month 20% off
Health coaching included with every plan
Money back if you do not lose 5% of body weight in 120 days

Pricing starts at

from $199/month

Visit Site Read full review

4.6Trustpilot(1,134)

SHED pairs compounded semaglutide (from $199/mo) and tirzepatide (from $299/mo) with included health coaching, 20% off month one and a 5%-in-120-days money-back guarantee. Trustpilot: 4.6 from 1,134 reviews.

Read full SHED review

Very Good

8.5out of 10

Prescription weight loss without the hassle

HSA/FSA approvedNo membership or hidden feesFree shipping

Treatments offered

Weekly semaglutide (GLP-1) injections · Weekly tirzepatide (GLP-1/GIP) injections · Daily oral dissolving GLP-1 tablets, no needles · Video visits, free dietitian access and care coaching

Starting price

$199$99/month

Semaglutide $99/mo · Tirzepatide $166/mo

Semaglutide (GLP-1) injections from $99/month (normally $199)
Tirzepatide (GLP-1/GIP) injections from $166/month (normally $299)
Needle-free daily dissolving GLP-1 tablets at $249/month
Video visits, free dietitian access and care coaching

Pricing starts at

from $99/month

Visit Site Read full review

4.3Trustpilot(14,987)

Medvi bundles provider visits, medication, free dietitian access and care coaching into one price: semaglutide from $99/mo (reg. $199), tirzepatide from $166/mo (reg. $299). HSA/FSA approved. Trustpilot: 4.3 from 14,987 reviews.

Read full Medvi review

Very Good

8.4out of 10

$200 off your first month of GLP-1 care

$200 off month oneShips within 2 daysPersonalized plans

Treatments offered

Compounded semaglutide injection (GLP-1) · Compounded tirzepatide injection (GLP-1 + GIP) · Brand-name Wegovy (semaglutide) pen · Personalized treatment plans guided by a provider

Starting price

$149/month

Semaglutide $149/mo · Tirzepatide $199/mo

*Compounded medications are not FDA-approved.

Semaglutide from $149/mo
Tirzepatide from $199/mo
Brand-name Wegovy from $1,799/mo
Prescriptions ship within 2 days

Pricing starts at

from $149/month

Visit Site Read full review

4.1Trustpilot(188)

Sprout offers personalized GLP-1 plans with compounded semaglutide from $149/mo, tirzepatide from $199/mo and brand-name Wegovy, and ships prescriptions within 2 days.

Read full Sprout review

Very Good

8.2out of 10

Get started today for $147

Treatments offered

Compounded semaglutide · Compounded tirzepatide · Dosing optimized by algorithm · Treatment changes informed by your data

Treatment matching driven by algorithms
Licensed provider consultations included
Personalized GLP-1 medication plans
Progress tracking based on your data

Visit Site Read full review

Wellorithm uses algorithms and patient data to recommend GLP-1 treatment plans, with licensed providers overseeing every prescription.

Read full Wellorithm review

How do GLP-1 weight loss injections work?

GLP-1 injections copy a natural hormone that lowers appetite, slows how quickly the stomach empties and helps control blood sugar. You give yourself one small injection under the skin each week, and most people find it fast and close to painless. Our GLP-1 medications guide explains the science.

Which weight loss injections are available?

There are two main injectable GLP-1 medications: semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound). Telehealth providers offer both in brand-name and compounded versions. Tirzepatide acts on two receptors and may produce larger results, while semaglutide has been in use longer. Compare them in our side-by-side guide.

Semaglutide: about 15% average weight loss
Tirzepatide: up to 22.5% average weight loss
One self-injection per week
Doses rise gradually to limit side effects

What happens after you start weight loss injections?

Most people notice appetite changes within the first two weeks and see meaningful weight loss by weeks 4-8. Side effects tend to show up around dose increases and usually ease with time. For a week-by-week timeline, read our first month guide and side effects guide.

How much do weight loss injections cost?

Brand-name GLP-1 injections cost $900-$1,400/month at retail. Compounded versions from telehealth providers usually run $49-$299/month, often with everything included. Our cost guide breaks down the numbers, and our quiz can match you with a provider in your budget.

Our rankings are rechecked on a rolling basis. For deeper research, read our weight loss guides, or answer a few quick questions to get a provider suggestion that fits your goals and budget.

Related GLP-1 guides

Every other weight loss medication guide on Top Weight Loss, each built on prices we have checked ourselves.

Best Weight Loss Injections of 2026

Injectable GLP-1 treatments, compared side by side

Semaglutide from $69/mo, delivered in 1-2 days

Low-cost GLP-1 care: semaglutide from $89/mo

Flat-price GLP-1: semaglutide $99/mo, tirzepatide $129/mo at every dose

Compounded semaglutide from $49/month and tirzepatide from $89/month

Online weight loss care from an established telehealth brand

Custom-dosed GLP-1 plans with ongoing provider check-ins

20% off your first month of GLP-1 treatment

Prescription weight loss without the hassle

$200 off your first month of GLP-1 care

Get started today for $147

How do GLP-1 weight loss injections work?

Which weight loss injections are available?

What happens after you start weight loss injections?

How much do weight loss injections cost?

Related GLP-1 guides

FAQs