GLP-1 Prices & Weight Loss Statistics: October 2026 Index
How much compounded semaglutide and tirzepatide cost at 9US telehealth providers, with each price checked on the provider’s own site and every change dated, alongside the published trial results for GLP-1 weight-loss medicines (STEP, SURMOUNT, SCALE). Free to cite.
Last price check October 16, 2026 · 4 changes recorded since September 14, 2026
Original Top Weight Loss research
How much does compounded GLP-1 cost per month? 9 providers surveyed
As of October 2026, compounded semaglutide costs $49 to $199 a month and compounded tirzepatide costs $89 to $299 a month across the 9 US telehealth providers we track. Brand-name versions of the same active ingredients carry four-figure list prices (table below). Each number is a price the provider itself publishes, checked by our team, never an estimate.
Brand medication
Active ingredient
Brand list price
Compounded from
Ozempic
Semaglutide
$1,149-$1,399/mo
$49/mo
Zepbound
Tirzepatide
$1,249-$1,599/mo
$89/mo
Wegovy
Semaglutide
$1,579-$1,799/mo
$49/mo
Source: Top Weight Loss GLP-1 price index covering 9 providers, published prices verified as of October 2026. Brand prices are manufacturer or pharmacy list prices, which insurance and manufacturer coupons can reduce. For a provider-by-provider breakdown, see our cheapest GLP-1 comparison.
Compounded semaglutide and tirzepatide prices by provider (9 providers, checked October 16, 2026)
Every row shows a provider’s headline monthly price together with the condition that applies to it, such as a promotional rate, a required plan length or a prepaid term. We never show a price without its condition. Rows run from the cheapest semaglutide price to the most expensive.
Compounded medicines are made by state-licensed pharmacies and are not FDA-approved. Each provider in the index requires a review by a licensed clinician before prescribing. All prices are cash prices, so check current terms on the provider’s own site.
How have GLP-1 prices changed? The change log
For the complete dated feed alongside each provider’s current listing, see GLP-1 price changes.
Whenever a price check alters a listing, we log the date, the previous listing and the new one. The most recent changes appear first.
September 21, 2026
altRx
altRx extended its sale on compounded semaglutide ($89/month) and tirzepatide ($149/month). The listed end date moved from September 20 to September 25; the prices themselves did not change.
September 15, 2026
TrimRx
TrimRx compounded semaglutide moved to $149/month at every dose, with a $140 discount applied. Our earlier listing showed $179 for month one and $299 a month after that. Tirzepatide stayed at $259/month.
September 14, 2026
altRx
We confirmed altRx's sale prices of $89/month for semaglutide and $149/month for tirzepatide, with a listed end date of September 20. The regular prices are still $199 and $299.
September 14, 2026
welludr
welludr lowered compounded semaglutide to $49/month on the 12-month plan (down from $59) and tirzepatide to $89/month (down from $99). Each price applies at every dose.
Our 2 favorite GLP-1 providers
The two providers our editors recommend first, with the same checked prices and scores used in our full ranking.
Our Most Popular
1
Exceptional
9.8out of 10
Semaglutide from $69/mo, delivered in 1-2 days
Refund if not approvedFree expedited shippingNo hidden fees
Treatments offered
Compounded semaglutide injection (GLP-1) · Compounded tirzepatide injection (GLP-1 + GIP) · Online doctor review and prescription · Dose changes through the patient portal
Starting price
$79$69/month
*Compounded medications are not FDA-approved.
Semaglutide $69/mo; tirzepatide $119/mo
5-minute questionnaire; doctor review usually within 24 hours
Free 1-2 day shipping: cold-packed, tracked and insured
embody prescribes compounded semaglutide at $69/mo and tirzepatide at $119/mo online, ships in 1-2 days, and requires no insurance. Trustpilot: 3.8 from 9,604 reviews.
altRx sells compounded semaglutide from $89/month and tirzepatide from $149/month at a flat price per dose, plus brand-name Ozempic, Zepbound and Wegovy. Self-pay, no insurance needed.
Source: the pivotal published trials, namely STEP 1 (Wilding et al., New England Journal of Medicine, 2021) for semaglutide 2.4mg, SURMOUNT-1 (Jastreboff et al., NEJM, 2022) for tirzepatide 15mg, SCALE (Pi-Sunyer et al., NEJM, 2015) for liraglutide 3mg, and the SUSTAIN program for semaglutide 2mg. These are trial averages, and individual results differ.
What are the most common GLP-1 side effects?
Side Effect
Semaglutide
Tirzepatide
Nausea
~40-44%
~25-33%
Diarrhea
~30%
~19-23%
Vomiting
~24%
~8-13%
Constipation
~23%
~12-17%
Source: FDA prescribing information and safety data from the pivotal STEP and SURMOUNT programs. Rates are approximate, and side effects usually ease over time and once the dose is stable.
How fast do you lose weight on a GLP-1?
Timeframe
Typical progress
Week 1-2
Smaller appetite, feeling full sooner, possibly mild nausea
Month 1
3-5 lbs lost on the starting dose
Month 2-3
~3-6% of body weight lost as the dose rises
Month 6
10-15% of body weight lost (semaglutide) or 15-20% (tirzepatide)
Month 12-16
Peak results: 15% (semaglutide) to 22.5% (tirzepatide)
Source: averages from clinical trials. Your results depend on the medication, dose, diet and exercise.
Who qualifies for GLP-1 weight loss medication?
Under FDA-approved prescribing criteria, GLP-1 weight loss medicines are indicated for adults who have:
A BMI of 30 or higher (obesity)
A BMI of 27 or higher plus at least one weight-related condition (type 2 diabetes, hypertension, high cholesterol, sleep apnea)
Who should avoid them
Semaglutide and tirzepatide both carry an FDA boxed warning for thyroid C-cell tumors, and neither should be used by anyone with a personal or family history of medullary thyroid carcinoma or MEN 2 syndrome. Clinicians use them cautiously after pancreatitis or gallbladder disease, and they are not used during pregnancy. Go over your full health history with a licensed clinician first.
Semaglutide outperforms older weight-loss drugs: in STEP 1, semaglutide 2.4 mg produced about 15% average weight loss compared with roughly 2.4% in the lifestyle-only (placebo) group, a much larger effect than earlier weight-loss medicines.
One injection a week: semaglutide and tirzepatide are both given as a once-weekly injection under the skin.
The dose rises slowly: treatment begins at a low dose that steps up each month over 16-20 weeks to keep side effects down.
Prescribed online: licensed telehealth providers can prescribe GLP-1 medicines after a fully online medical evaluation and deliver to your home in most US states.
Stopping brings weight back: in the STEP 1 extension, people regained about two-thirds of the weight they had lost within a year of stopping semaglutide, which supports long-term treatment.
Tirzepatide works on two receptors: it acts on both GLP-1 and GIP receptors, which may explain why it outperforms semaglutide on weight loss.
How we collect this data, and how to cite it
Pricing: we follow the compounded semaglutide and tirzepatide prices that 9US telehealth providers publish. Our team checks each figure against the provider’s own site, and we never estimate, model or extrapolate a price. The most recent check was on October 16, 2026, and any change to a listing goes into the dated change log above.
Clinical data:the weight-loss and side-effect numbers come from each medicine’s pivotal published trials (STEP, SURMOUNT, SCALE, SUSTAIN) and FDA prescribing information. They are trial averages, not a promise of what any one person will achieve.
Want to cite this data?Credit “Top Weight Loss GLP-1 Price Index (2026)” and link back to this page. For a provider-by-provider pricing comparison, see our cheapest GLP-1 comparison. This page offers general information and is not medical advice.
Related GLP-1 guides
Every other weight loss medication guide on Top Weight Loss, each built on prices we have checked ourselves.
