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Guide6 min read

TrimRx Cost (2026): $149 Semaglutide, No Contract

TrimRx (Trim Rx) charges $149/month for semaglutide at every dose and $259 for tirzepatide, no contract. How its discounts work and what a year costs ($1,788).

Last updated September 15, 2026

Francheska Capistrano, Medical Content Reviewer

Francheska Capistrano, RMT, MPH

Clinically checked · Our review process

Key points

  • TrimRx charges $149/month for compounded semaglutide (with a $140 discount already applied, same price at every dose) and $259/month for tirzepatide. Medication, consultations and clinical support are included.
  • There is no long-term contract. You pay the listed rate month to month and can stop at any renewal, or choose a multi-month plan for a lower rate, a decision made at each renewal rather than at signup.
  • A year of month-to-month semaglutide costs $1,788, roughly $1,200 more than welludr's locked $588. That gap is what flexibility costs.
  • For tirzepatide, DirectMeds' flat $147 is $112/month below TrimRx's $259, a difference that grows quickly.

How much does TrimRx cost per month?

Quick answerTrimRx (Trim Rx) charges $149 a month for compounded semaglutide, which already includes a $140 discount and stays the same at every dose, and $259 a month for tirzepatide. Both prices include medication, provider consultations and ongoing clinical support. There is no long-term contract, and multi-month plans lower the monthly rate further.

TrimRx is self-pay, uses no insurance, and runs 100% online. The basic choice: stay month to month at $149 and keep the freedom to stop, or commit several months at once for a lower rate. TrimRx is unusual in letting you make that choice at each renewal instead of only at signup.

Trustpilot at a glance

TrimRx is rated 3.8 out of 5 from 5,392 reviews on its public Trustpilot page. We saved 23 of those reviews word for word (dated Jul 17, 2026 to Sep 24, 2026). They break down as 17 5-star, 1 4-star, 1 3-star and 4 2-star, so 78% give 4 or 5 stars and 17% give 1 or 2 stars. All of them appear below, the lowest-rated included, with reviewer names shortened.

5 star
17 (74%)
4 star
1 (4%)
3 star
1 (4%)
2 star
4 (17%)
1 star
0 (0%)
TrimRx logo

TrimRx customer reviews on

Trustpilot
(5,392 reviews)

Showing all 23 reviews we saved, every 2-star review included.

Sort
Sep 24, 2026

Priced fairly and easy to use

“Priced fairly and easy to use”

J

Jerald W.

US

Sep 24, 2026

Screening was more thorough than I...

“Screening was more thorough than I expected and the communication has not dropped off since. Two other places went quiet right after payment.”

J

Jean B.

US

Sep 24, 2026

Support replies fast and nothing felt...

“Support replies fast and nothing felt rushed, super”

M

Mary O.

US

Sep 23, 2026

The company I used before charged me...

“The company I used before charged me every month and never sent anything. Then a separate shipper billed me again for a package that never showed up. I'm still chasing that money and I've mostly given up on it. What's different this time is how many emails TrimRx sends without me asking. Order confirmed, prescription written, label created, out for delivery, four messages in five days.”

N

Narine P.

US

Sep 23, 2026

The box is labeled plainly

“The box is labeled plainly, nothing that gives it away on the porch, thanks!!”

N

Nicholas H.

US

Sep 23, 2026

My old provider was charging me close...

“My old provider was charging me close to double this!”

S

Sharon B.

US

Sep 23, 2026

Communication has been the strong point

“Communication has been the strong point”

J

James M.

US

Sep 23, 2026

The intake was clear

“The intake was clear, I never had to guess at a question, and getting from submitted to approved took no time at all.”

H

Herminia L.

US

Sep 23, 2026

Clear pricing

“Clear pricing, no hand holding needed.”

A

Alain

US

Sep 23, 2026

Shipping runs two or three days and the...

“Shipping runs two or three days and the box arrives cold.”

J

Jaime D.

US

Aug 3, 2026

I started my weight loss journey on May 1st

“I started my weight loss journey on May 1st. I have lost 41 lbs. It's more than just the weight loss. The things you used to think were fun like gambling, drinking, and smoking no longer are rewarding. Spending time with my grandson now - that's a good time. My mental clarity has so improved. My high blood pressure is gone. I'm happier than I've been in years. The Trizepatide with B12 from TrimRx really works! I've still got another 50 lbs to go. If you're skeptical about GLP-1s, don't be.”

S

Steve T.

US

Jul 28, 2026

Excellent customer service

“Cynthia reached out not long after I had gone through the online process. She was very kind and helpful and understanding that I was looking to find the best support and costs for my weightloss. Ultimately I decided to fight my Dr, but for those that need good support along the way you cant go wrong using Trim Rx.”

K

Katrina C.

US

Jul 18, 2026

I opened the first box yesterday

“I opened the first box yesterday, everything was there and properly sealed. A good start.”

L

Lisa C.

US

Jul 18, 2026

Just took my 3rd injection

“Just took my 3rd injection. Down 4 pounds so far, it's been a good experience.”

N

Nichole Y.

US

Jul 18, 2026

Payment went through without any problems

“Payment went through without any problems and the box arrived exactly when they promised. Everything correct.”

J

Jessica J.

US

Jul 18, 2026

They got back to me the same day

“I had a question and they got back to me the same day. Friendly and to the point.”

N

Nadia T.

US

Jul 17, 2026

The provider went through my health history

“The provider went through my health history before approving the prescription. I didn't feel rushed through it.”

A

Alejandro A.

US

Sep 21, 2026

Whoever was helping me answered my...

“Whoever was helping me answered my questions and followed up after, and communication has been solid the whole way. My one gripe is it was supposed to arrive in 48 hours and it actually took 5 days.”

M

Michael H.

US

Sep 22, 2026

The price runs a little high

“The price runs a little high, but if the quality holds I don't mind paying it. Delivery has been great every time and the whole thing is easy to follow. So far it's going well. The only frustrating part is those weeks where the scale just sits, though I knew that would happen.”

T

Tiffany C.

US

Sep 23, 2026

The tracking date moved twice and the...

“The tracking date moved twice and the box came three days late, and the cold packs were warm to the touch when I finally opened it.”

H

Holly H.

US

Sep 23, 2026

The medication was not working for me

“The medication was not working for me, so I canceled my prescription but I am still receiving text and emails from Affirm saying they have not received cancellation from trim rx and is trying to continue charging me each month.”

G

George L.

US

Sep 21, 2026

Unreliable! Potentially crooks!

“The onboarding process was fine, telehealth etc. They processed my order AND full payment very quickly. I signed up for a 6-month plan which delivers in two deliveries. First upon approval and second 3 months later. I've not received the second order; which I already paid for, and it's over 30 days late. They do not respond on their website chat or answer the phone when called. I've been trying to contact someone for 10 days. I finally ended up disputing with my CC company.”

K

Karen A.

US

Sep 20, 2026

This is my first order with TrimRX

“This is my first order with TrimRX. I've not even received the order and I'm already having problems. The RX that was sent to my patient portal was not even me. I tried to reach out via chat....nothing. Email? No response. The phone call was automated and someone should be reaching out to me soon. I've yet to hear back. Email codes are not being received by me and the charge on my next bill is double what they'd told me initially. $399 for a month of Tirzepatide? I could purchase Mounjaro for less. In the meantime....rx has been shipped out without anyone contacting me about the incorrect rx information. Very very dissatisfied and will not be ordering from them again. Too much of a hassle.”

M

Mrs V

US

1 / 23

Each review is quoted word for word from a public Trustpilot page, with the reviewer’s name shortened. It reflects one customer’s experience: a weight-loss result someone mentions is personal, not typical, and your results may differ. Trustpilot is a trademark of Trustpilot A/S, which has no affiliation with Top Weight Loss.

TrimRx vs Medvi and five others at the mid-market price point

TrimRx's $149 semaglutide now competes with Medvi's $99 promotional price, and the two sell almost opposite things:

  • Medvi spends on high-touch care: video visits, a dietician, coaching, and a 4.3 Trustpilot rating from 14,987 reviews.
  • TrimRx spends on flexibility: no contract, optional discounts and a leaner clinical-support model.

Which one is better depends on what you value. The full comparison is in Medvi vs TrimRx.

ProviderSemaglutideTirzepatideModel
welludr$49/mo$89/mo12-mo lock for best rate
embody$69/mo$119/moFlat, no commitment
altRx$89/mo$149/moFlat + brand shelf
HealthRx$99/mo*from $17912-mo prepaid
DirectMeds$147/mo$147/moFlat, drops option
TrimRx$149/mo$259/moNo contract, opt-in discounts
Medvi$99/mo promo (reg. $199)$166/mo promo (reg. $299)All-inclusive high-touch

*prepaid annual. Check the tirzepatide column: DirectMeds is $112 a month cheaper than TrimRx's $259. If tirzepatide is your medication, that gap adds up fast.

Semaglutide plans and prices by provider

Each provider's published semaglutide plan, sorted from lowest price, with the terms listed under every price.

How TrimRx's multi-month discount works at renewal

TrimRx rewards commitment without requiring it. Here is how the pricing works:

  • Month to month: you pay the listed $149 or $259 and can stop at any renewal.
  • Multi-month plan: the monthly rate drops below the listed price. Exact rates appear at signup and depend on plan length.

Most patients miss that you can do both, in order. Start month to month while you and your clinician confirm that the medication and dose suit you; the first 8-12 weeks usually settle that. Then move to a multi-month rate once the uncertainty is gone. You pay a small premium only during the months when flexibility is valuable.

To estimate when your own uncertainty ends, see the titration timeline in how long semaglutide takes to work.

Is $1,788 a year at TrimRx worth it?

A year of month-to-month semaglutide at TrimRx costs $1,788. Against welludr's locked $588, flexibility costs about $1,200 a year.

Paying for flexibility makes sense when your situation might really change: uncertain income, a possible move to brand-name medication, or early months spent confirming the medication works for you.

It does not make sense forever. Once you know you are staying, take TrimRx's multi-month discount or move to a cheaper provider. Paying for flexibility you no longer need is money with nothing in return.

→ Current TrimRx plans and multi-month rates

This article is general information, not medical advice. Prices are as listed when we wrote this; confirm current pricing on the provider's site.

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References and clinical sources

The medication facts on this page rest on FDA guidance and peer-reviewed clinical trials, while prices and plan terms come from what each provider publishes. Use this page as general information, not medical advice, and speak with a licensed clinician before you start any weight loss treatment.

  1. 1.Once-Weekly Semaglutide in Adults with Overweight or Obesity (STEP 1 trial) - New England Journal of Medicine, 2021
  2. 2.Tirzepatide Once Weekly for the Treatment of Obesity (SURMOUNT-1 trial) - New England Journal of Medicine, 2022
  3. 3.FDA Approves New Drug Treatment for Chronic Weight Management (semaglutide / Wegovy) - U.S. Food & Drug Administration, 2021
  4. 4.FDA Approves New Medication for Chronic Weight Management (tirzepatide / Zepbound) - U.S. Food & Drug Administration, 2023
  5. 5.FDA's Concerns with Unapproved GLP-1 Drugs Used for Weight Loss - U.S. Food & Drug Administration
  6. 6.Human Drug Compounding (503A pharmacy standards) - U.S. Food & Drug Administration
  7. 7.Semaglutide Injection - drug information - MedlinePlus, U.S. National Library of Medicine (NIH)